International Antiaging Systems
XANTHINOL NICOTINATE
Xanthinol Nicotinate (XN) is a form of Niacin that passes easily through cell membranes; XN is the most potent form of Niacin available.
XN has been shown to increase brain glucose metabolism, improve brain ATP levels and improve brain blood flow (it acts as a vasodilator). As such, XN has been used to treat short-term memory disorders, mental flagging (i.e. lack of brain energy that compromises vigilance, concentration and attention) and insufficient blood flow to the arteries and the extremities. Furthermore XN has been clinically shown to improve the reaction speed of the elderly.
XN (like Niacin) can cause a flushing of the skin and a sense of warmth; it has therefore been suggested that XN can aid weight control through water loss. However we would suggest that XN be used for this purpose only prior to exercise or prior to climbing into a hot tub. This is in order to minimize the flushing affects that may be uncomfortable for some people.
XN can be used as an anti-aging memory support at 1 or 2 tablets (150mg each) three times a day, to a maximum of 12 tablets (1800mg total) prior to a workout or exercise.
Caution: build up to high doses gradually, XN at high doses can cause blood pressure changes and must therefore be avoided by persons suffering from peptic ulcers, liver problems, severe hypotension, myocardial infarction or other congestive heart problems.
At lower doses some minor side effects such as flushing, nausea, heartburn, itchy skin or vomiting (rare) may present themselves, these normally dissipate with a lower dose or continued use.
"Xanthinol Nicotinate significantly improved reaction times in elderly subjects"
S. M. Loriaux, J.B. Deijen, J.F. Orlebeke, J.H. DeSwart"The effect of Niacin and Xanthinol Nicotinate on human memory in different age categories"
Psychopharmacology, Vol. 87, 1985 390-395."Xanthinol appears to me to keep my mind clear and my body trim! I believe that these Niacin derivatives are key elements as recent reports about NADH attest to."
G.S., Arizona.