International Antiaging Systems

NOOTROPICS
  read James South's nootropics article


Nootropic means "acting on the mind", It is a term given to the first substance found to have beneficial effects in the treatment of memory loss, age related memory decline, lack of concentration, etc. That substance was piracetam (Nootropil®). Not only was it beneficial, but it was also found to have so few side effects that one biochemist described it "as safe as salt!"

"The racetam Nootropics may literally be safe and effective pharmacologic tools to enhance, protect and optimize truly normal, fully human neuropsychological structures and function, well into old age." James South MA.

The current available list of nootropics comprises of:

ANIRACETAM (Draganon®)
Aniracetam improves memory recall, reaction and detail.  Like all of piracetam's analogues it is more potent.  In tests aniracetam has proven to be one of the most potent nootropics currently available because of its ability to protect AMPA brain receptors and nerve cells. Normal doses are considered to be one or two tablets (750mg each) per day (see notes at base of Nootropic section).

"Nootropics may increase learning and memory in healthy individuals through a distinctive power to promote what has been termed hemispheric-super-connection" S.J. Dimond et al , "Effects of nootropics" Psycopharmacol. 64, 1979 341-348.

OXIRACETAM (Neuromet®)
Oxiracetam, is the closet derivative of piracetam and is used in the industry as the nootropic standard (in other words, when new Nootropics are designed they are compared to oxiracetam). Like all the analogues Oxiracetam is more potent mg dose / Kg bodyweight when compared to Piracetam.
Oxiracetam doses are 1 tablet (800mg each) twice daily (see notes at base of Nootropic section).

"Oxiracetam is the industry standard nootropic drug, when new nootropics are developed they are often compared not to the first nootropic- Piracetam, but in fact to its first analogue- Oxiracetam" Phil Micans PharmB, Great Britain

PIRACETAM
This is the piracetam developed by the UCB company and branded Nootropil®. IAS believes that this product remains the best quality piracetam on a market now infiltrated with generics.
Usual starting doses are considered "attack" at two tablets (1200mg each) twice a day, lowering to one tablet twice a day after a month (see notes at base of Nootropic section).

"the fact is that Piracetam improves verbal learning and appears to be a substance capable of extending the intellectual functions of man, even individuals already gifted with high intelligence and good memory" S.J. Dimond, E. Brouwers, "Increase in the power of human memory in normal man through the use of drugs" Psychopharmacol. 49, 1976, 307-309.

PRAMIRACETAM (NeuPramir®)
Recent clinical trials would indicate that pramiracetam might be the most potent piracetam analogue.  One clinical trial described optimum piracetam dosages at 100mg per Kg body weight, whereas pramiracetam was 15mg/ Kg body weight, effectively up to 7 times stronger.  Regular doses of pramiracetam are one tablet (600mg each) once or twice daily (see notes at base of Nootropic section).

"Pramiracetam has proven more effective than Piracetam in the treatment of Alzheimer's disease, perhaps not surprisingly when Pramiracetam has been shown to be up-to 15 times more powerful than Piracetam mg/ mg." Smart Drugs and Nutrients, Smart Publications, Petaluma, California.

HOME